Ontology highlight
ABSTRACT:
SUBMITTER: Clague J
PROVIDER: S-EPMC3640857 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Clague Jessica J Lippman Scott M SM Yang Hushan H Hildebrandt Michelle A T MA Ye Yuanqing Y Lee J Jack JJ Wu Xifeng X
Molecular carcinogenesis 20100201 2
MicroRNAs (miRNAs) have been reported to play a key role in oncogenesis and, recently, studies have examined the role miRNAs might play in the risk of premalignant lesions. To our knowledge, no study has investigated the association between miRNA polymorphisms and risk of oral premalignant lesions (OPLs). We genotyped 31 single nucleotide polymorphisms (SNPs) among 21 miRNA-related genes in a case-control study including 136 OPL patients and 136 matched controls. Patients with at least one varia ...[more]