Missing data and influential sites: choice of sites for phylogenetic analysis can be as important as taxon sampling and model choice.
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ABSTRACT:
SUBMITTER: Shavit Grievink L
PROVIDER: S-EPMC3641631 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Publications
Missing data and influential sites: choice of sites for phylogenetic analysis can be as important as taxon sampling and model choice.
Shavit Grievink Liat L Penny David D Holland Barbara R BR
Genome biology and evolution 20130101 4
Phylogenetic studies based on molecular sequence alignments are expected to become more accurate as the number of sites in the alignments increases. With the advent of genomic-scale data, where alignments have very large numbers of sites, bootstrap values close to 100% and posterior probabilities close to 1 are the norm, suggesting that the number of sites is now seldom a limiting factor on phylogenetic accuracy. This provokes the question, should we be fussy about the sites we choose to include ...[more]
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