Ontology highlight
ABSTRACT:
SUBMITTER: Hellen EH
PROVIDER: S-EPMC3642084 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
PloS one 20130502 5
We investigate the dynamics of a synthetic genetic repressilator with quorum sensing feedback. In a basic genetic ring oscillator network in which three genes inhibit each other in unidirectional manner, an additional quorum sensing feedback loop stimulates the activity of a chosen gene providing competition between inhibitory and stimulatory activities localized in that gene. Numerical simulations show several interesting dynamics, multi-stability of limit cycle with stable steady-state, multi- ...[more]