Ontology highlight
ABSTRACT:
SUBMITTER: Huang P
PROVIDER: S-EPMC3645870 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
Huang Peng P Lin Jing J Wang Shouju S Zhou Zhijun Z Li Zhiming Z Wang Zhe Z Zhang Chunlei C Yue Xuyi X Niu Gang G Yang Min M Cui Daxiang D Chen Xiaoyuan X
Biomaterials 20130322 19
Multifunctional theranostics have recently been intensively explored to optimize the efficacy and safety of therapeutic regimens. In this work, a photo-theranostic agent based on chlorin e6 (Ce6) photosensitizer-conjugated silica-coated gold nanoclusters (AuNCs@SiO2-Ce6) is strategically designed and prepared for fluorescence imaging-guided photodynamic therapy (PDT). The AuNCs@SiO2-Ce6 shows the following features: i) high Ce6 photosensitizer loading; ii) no non-specific release of Ce6 during i ...[more]