Ontology highlight
ABSTRACT:
SUBMITTER: Bianco IH
PROVIDER: S-EPMC3647252 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Bianco Isaac H IH Ma Leung-Hang LH Schoppik David D Robson Drew N DN Orger Michael B MB Beck James C JC Li Jennifer M JM Schier Alexander F AF Engert Florian F Baker Robert R
Current biology : CB 20120614 14
<h4>Background</h4>Although adult vertebrates sense changes in head position by using two classes of accelerometer, at larval stages zebrafish lack functional semicircular canals and rely exclusively on their otolithic organs to transduce vestibular information.<h4>Results</h4>Despite this limitation, we find that larval zebrafish perform an effective vestibulo-ocular reflex (VOR) that serves to stabilize gaze in response to pitch and roll tilts. By using single-cell electroporations and targete ...[more]