Ontology highlight
ABSTRACT:
SUBMITTER: Li D
PROVIDER: S-EPMC3648018 | biostudies-literature | 2013 May
REPOSITORIES: biostudies-literature
Li Dongju D Wang Xueqin X Wang Lu L Zhou Daoguo D
Infection and immunity 20130225 5
Salmonella enterica serovar Typhimurium depends on type III secretion systems to inject effector proteins into host cells to promote bacterial invasion and to induce intestinal inflammation. SipA, a type III effector, is known to play important roles in both the invasion and the elicitation of intestinal inflammation. The actin-modulating activity of SipA has been shown to promote Salmonella entry into epithelial cells. To investigate whether the actin-modulating activity of SipA is required for ...[more]