Ontology highlight
ABSTRACT:
SUBMITTER: Anderson M
PROVIDER: S-EPMC3650044 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
PloS one 20130509 5
Branchial arches are externally visible tissue bands in the head region of all vertebrate embryos. Although initially formed from similar components, each arch will give rise to different head and neck structures. In a screen designed to characterize the molecular control of branchial arch identity in mouse, we identified Pcp4 as a second branchial arch-specific molecular signature. We further show that the transcription factor Hoxa2 binds to Pcp4 chromatin and regulates Pcp4 expression in the s ...[more]