Ontology highlight
ABSTRACT:
SUBMITTER: Volk DW
PROVIDER: S-EPMC3650113 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
Schizophrenia research 20130402 1
Adolescent cannabis use is associated with greater relative risk, increased symptom severity, and earlier age of onset of schizophrenia. We investigated whether this interaction may be partly attributable to disease-related disturbances in metabolism of the major cortical endocannabinoid 2-arachidonoylglycerol (2-AG). Transcript levels for the recently discovered 2-AG metabolizing enzyme, α-β-hydrolase domain 6 (ABHD6), were assessed using quantitative PCR in the prefrontal cortex of schizophren ...[more]