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VP292 of White spot syndrome virus Interacts with VP26.

ABSTRACT: Interactions between virus structural proteins are suggested to be crucial for virus assembly. Many steps in the process of white spot syndrome virus (WSSV) assembly and maturation remain unclear. In this paper, we discovered a new interaction of WSSV VP292. Temporal-transcription analysis showed that VP292 is expressed in the late stage of WSSV infection. Western blot and matrix-assisted laser desorption ionization MS assays showed that VP292 interacts with VP26, a major envelope protein. Far-western blot provided further evidence for interaction between VP292 and VP26. These results collectively demonstrated that VP292 anchors to the envelope through interaction with VP26.

SUBMITTER: Li Q

PROVIDER: S-EPMC3650189 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature

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VP292 of White spot syndrome virus Interacts with VP26.

Li Qian Q Liu Qing-Hui QH Huang Jie J

Indian journal of virology : an official organ of Indian Virological Society 20121216 1

Interactions between virus structural proteins are suggested to be crucial for virus assembly. Many steps in the process of white spot syndrome virus (WSSV) assembly and maturation remain unclear. In this paper, we discovered a new interaction of WSSV VP292. Temporal-transcription analysis showed that VP292 is expressed in the late stage of WSSV infection. Western blot and matrix-assisted laser desorption ionization MS assays showed that VP292 interacts with VP26, a major envelope protein. Far-w ...[more]

PMID: 24426258

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