Ontology highlight
ABSTRACT:
SUBMITTER: Pols TW
PROVIDER: S-EPMC3650458 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Pols Thijs W H TW Noriega Lilia G LG Nomura Mitsunori M Auwerx Johan J Schoonjans Kristina K
Journal of hepatology 20101209 6
Bile acids (BAs) are amphipathic molecules that facilitate the uptake of lipids, and their levels fluctuate in the intestine as well as in the blood circulation depending on food intake. Besides their role in dietary lipid absorption, bile acids function as signaling molecules capable to activate specific receptors. These BA receptors are not only important in the regulation of bile acid synthesis and their metabolism, but also regulate glucose homeostasis, lipid metabolism, and energy expenditu ...[more]