EQTL Mapping Using RNA-seq Data.
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ABSTRACT:
SUBMITTER: Sun W
PROVIDER: S-EPMC3650863 | biostudies-literature | 2013 May
REPOSITORIES: biostudies-literature
Publications
As RNA-seq is replacing gene expression microarrays to assess genome-wide transcription abundance, gene expression Quantitative Trait Locus (eQTL) studies using RNA-seq have emerged. RNA-seq delivers two novel features that are important for eQTL studies. First, it provides information on allele-specific expression (ASE), which is not available from gene expression microarrays. Second, it generates unprecedentedly rich data to study RNA-isoform expression. In this paper, we review current method ...[more]
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