Ontology highlight
ABSTRACT:
SUBMITTER: Holliday EG
PROVIDER: S-EPMC3651583 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Nature genetics 20120902 10
Genome-wide association studies (GWAS) have not consistently detected replicable genetic risk factors for ischemic stroke, potentially due to etiological heterogeneity of this trait. We performed GWAS of ischemic stroke and a major ischemic stroke subtype (large artery atherosclerosis, LAA) using 1,162 ischemic stroke cases (including 421 LAA cases) and 1,244 population controls from Australia. Evidence for a genetic influence on ischemic stroke risk was detected, but this influence was higher a ...[more]