Ontology highlight
ABSTRACT:
SUBMITTER: Wilson NR
PROVIDER: S-EPMC3653570 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Wilson Nathan R NR Runyan Caroline A CA Wang Forea L FL Sur Mriganka M
Nature 20120801 7411
Brain circuits process information through specialized neuronal subclasses interacting within a network. Revealing their interplay requires activating specific cells while monitoring others in a functioning circuit. Here we use a new platform for two-way light-based circuit interrogation in visual cortex in vivo to show the computational implications of modulating different subclasses of inhibitory neurons during sensory processing. We find that soma-targeting, parvalbumin-expressing (PV) neuron ...[more]