Ontology highlight
ABSTRACT:
SUBMITTER: Zhang H
PROVIDER: S-EPMC3653976 | biostudies-literature | 2013 May
REPOSITORIES: biostudies-literature
Zhang Hongbin H Patel Alpesh A Gaharwar Akhilesh K AK Mihaila Silvia M SM Iviglia Giorgio G Mukundan Shilpaa S Bae Hojae H Yang Huai H Khademhosseini Ali A Khademhosseini Ali A
Biomacromolecules 20130401 5
Hyperbranched polyesters (HPE) have a high efficiency to encapsulate bioactive agents, including drugs, genes, and proteins, due to their globe-like nanostructure. However, the use of these highly branched polymeric systems for tissue engineering applications has not been broadly investigated. Here, we report synthesis and characterization of photocrosslinkable HPE hydrogels with sustained drug release characteristics for cellular therapies. These HPE can encapsulate hydrophobic drug molecules w ...[more]