Hepatitis C virus infection: looking for interferon free regimens.

ABSTRACT: Recent developments of new drugs' combinations are changing the treatment paradigm in hepatitis C virus infection. Due to the side effect profile of pegylated interferons, interferon-sparing regimens have become the main target in chronic hepatitis C treatment research. Recent proofs of concept studies have suggested that cure of chronic hepatitis C can be achieved without interferon. The purpose of this paper is to provide an overview of the clinical results recently reported for the treatment of hepatitis C virus infection with interferon-free regimens, focusing on the most promising new compounds and combinations.

SUBMITTER: Gonzalez-Moreno J 

PROVIDER: S-EPMC3654259 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature