Genome-wide association study of antibody response to Newcastle disease virus in chicken.

ABSTRACT:

Background

Since the first outbreak in Indonesia in 1926, Newcastle disease has become one of the most common and contagious bird diseases throughout the world. To date, enhancing host antibody response by vaccination remains the most efficient strategy to control outbreaks of Newcastle disease. Antibody response plays an important role in host resistance to Newcastle disease, and selection for antibody response can effectively improve disease resistance in chickens. However, the molecular basis of the variation in antibody response to Newcastle disease virus (NDV) is not clear. The aim of this study was to detect genes modulating antibody response to NDV by a genome-wide association study (GWAS) in chickens.

Results

To identify genes or chromosomal regions associated with a

SUBMITTER: Luo C 

PROVIDER: S-EPMC3654938 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature