Hypoestrogenic "inactive phases" at the start of the menstrual cycle: changes with age and reproductive stage, and relationship to follicular depletion.

ABSTRACT:

Objective

To investigate hypoestrogenic "inactive phases" (IP) in the follicular phase of the menstrual cycle, with respect to age, reproductive stage, and follicular depletion.

Design

Analysis of prospectively collected menstrual bleed and estrone-3-glucuronide data.

Setting

Center for Population and Health, Georgetown University.

Patient(s)

White women (n = 88, aged 25-59 years, mean = 44.7 years) from the population-based Biodemographic Models of Reproductive Aging (BIMORA) project.

Intervention(s)

None.

Main outcome measure(s)

The IP durations by age and reproductive stage. Estimated follicular depletion rate based on IP durations.

Result(s)

Mean IP duration and variability decreased and then increased with age/reproductive stage. The p

SUBMITTER: Ferrell RJ 

PROVIDER: S-EPMC3655429 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature