Bacterial response regulators: versatile regulatory strategies from common domains.
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ABSTRACT:
SUBMITTER: Gao R
PROVIDER: S-EPMC3655528 | biostudies-literature | 2007 May
REPOSITORIES: biostudies-literature
Publications
Bacterial response regulators: versatile regulatory strategies from common domains.
Gao Rong R Mack Timothy R TR Stock Ann M AM
Trends in biochemical sciences 20070412 5
Response regulators (RRs) comprise a major family of signaling proteins in prokaryotes. A modular architecture that consists of a conserved receiver domain and a variable effector domain enables RRs to function as phosphorylation-regulated switches that couple a wide variety of cellular behaviors to environmental cues. Recently, advances have been made in understanding RR functions both at genome-wide and molecular levels. Global techniques have been developed to analyze RR input and output, exp ...[more]
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