Therapeutic vaccination to treat chronic infectious diseases: current clinical developments using MVA-based vaccines.
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ABSTRACT:
SUBMITTER: Boukhebza H
PROVIDER: S-EPMC3656061 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
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Therapeutic vaccination to treat chronic infectious diseases: current clinical developments using MVA-based vaccines.
Boukhebza Houda H Bellon Nadine N Limacher Jean Marc JM Inchauspé Geneviève G
Human vaccines & immunotherapeutics 20120816 12
A famous milestone in the vaccine field has been the first successful vaccination against smallpox, in 1798, by Edward Jenner. Using the vaccinia cowpox virus, Jenner was able to protect vaccinees from variola or smallpox. The Modified Virus Ankara (MVA) poxvirus strain has been one of the vaccines subsequently developed to prevent smallpox infection and was selected by the US government in their Biodefense strategy. Progress in molecular biology and immunology associated with MVA infection has ...[more]
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