Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Q
PROVIDER: S-EPMC3657317 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Zhang Qinfen Q Dai Xinghong X Cong Yao Y Zhang Junjie J Chen Dong-Hua DH Dougherty Matthew T MT Wang Jiangyong J Ludtke Steven J SJ Schmid Michael F MF Chiu Wah W
Structure (London, England : 1993) 20130401 4
Hemocyanins are responsible for transporting O2 in the arthropod and molluscan hemolymph. Haliotis diversicolor molluscan hemocyanin isoform 1 (HdH1) is an 8 MDa oligomer. Each subunit is made up of eight functional units (FUs). Each FU contains two Cu ions, which can reversibly bind an oxygen molecule. Here, we report a 4.5 A° cryo-EM structure of HdH1. The structure clearly shows ten asymmetric units arranged with D5 symmetry. Each asymmetric unit contains two structurally distinct but chemica ...[more]