A dense network of dendritic cells populates the murine epididymis.
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ABSTRACT:
SUBMITTER: Da Silva N
PROVIDER: S-EPMC3657760 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
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A dense network of dendritic cells populates the murine epididymis.
Da Silva Nicolas N Cortez-Retamozo Virna V Reinecker Hans-Christian HC Wildgruber Moritz M Hill Eric E Brown Dennis D Swirski Filip K FK Pittet Mikael J MJ Breton Sylvie S
Reproduction (Cambridge, England) 20110210 5
One of the most intriguing aspects of male reproductive physiology is the ability to generate spermatogenic cells - which are 'foreign' to the host - without triggering immune activation. After leaving the testis, spermatozoa enter the epididymis where they mature and are stored. In this study, we report a previously unrecognized dense network of dendritic cells (DCs) located at the base of the epididymal epithelium. This network was detected in transgenic mice expressing CD11c-EYFP and CX3CR1-G ...[more]
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