Ontology highlight
ABSTRACT:
SUBMITTER: Liu H
PROVIDER: S-EPMC3658002 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Liu Huijie H Wang Xueren X Wang Horng-Dar HD Wu Jinjing J Ren Jing J Meng Lingfeng L Wu Qingfa Q Dong Hansheng H Wu Jing J Kao Tzu-Yu TY Ge Qian Q Wu Zheng-xing ZX Yuh Chiou-Hwa CH Shan Ge G
Nature communications 20120101
Food and other environmental factors affect gene expression and behaviour of animals. Differences in bacterial food affect the behaviour and longevity of Caenorhabditis elegans. However, no research has been carried out to investigate whether bacteria could utilize endogenous RNAs to affect C. elegans physiology. Here we show that two Escherichia coli endogenous noncoding RNAs, OxyS and DsrA, impact on the physiology of C. elegans. OxyS downregulates che-2, leading to impairment in C. elegans ch ...[more]