Ontology highlight
ABSTRACT:
SUBMITTER: Parikh RY
PROVIDER: S-EPMC3659125 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Parikh Rasesh Y RY Kim Harold D HD
PloS one 20130520 5
Nucleosomes, which are the basic packaging units of chromatin, are stably positioned in promoters upstream of most stress-inducible genes. These promoter nucleosomes are generally thought to repress gene expression due to exclusion; they prevent transcription factors from accessing their target sites on the DNA. However, the role of promoter nucleosomes that do not directly occlude transcription factor binding sites is not obvious. Here, we varied the stability of a non-occluding nucleosome posi ...[more]