Narcolepsy with cataplexy mimicry: the strange case of two sisters.
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SUBMITTER: Pizza F
PROVIDER: S-EPMC3659383 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
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Narcolepsy with cataplexy mimicry: the strange case of two sisters.
Pizza Fabio F Vandi Stefano S Poli Francesca F Moghadam Keivan Kaveh KK Franceschini Christian C Bellucci Claudia C Cipolli Carlo C Ingravallo Francesca F Natalini Giuliana G Mignot Emmanuel E Plazzi Giuseppe G
Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20130615 6
We report on two sisters, 17 and 12 years of age, with clinical features suggesting narcolepsy with cataplexy (NC): daytime sleepiness, spontaneous and emotionally triggered sudden falls to the ground, and overweight/obesity. MSLT showed borderline sleep latency, with 1 and 0 sleep onset REM periods. HLA typing disclosed the DQB1*0602 allele. Video-polygraphy of the spells ruled out NC diagnosis by demonstrating their easy elicitation by suggestion, with wake EEG, electromyographic persistence o ...[more]
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