Ontology highlight
ABSTRACT:
SUBMITTER: Stanek J
PROVIDER: S-EPMC3659411 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Stanek Jan J Saxena Saurabh S Geist Leonhard L Konrat Robert R Koźmiński Wiktor W
Angewandte Chemie (International ed. in English) 20130320 17
An ultra-high-resolution NMR experiment for the measurement of intraresidue (1)H(i)-(15)N(i)-(13)C'(i) dipolar-chemical shift anisotropy relaxation interference is employed to extract information about local backbone geometries in intrinsically disordered proteins. The study of tumor suppressor BASP1 revealed a population shift of β-turn geometries at low pH conditions and a compaction of the BASP1 structural ensemble. ...[more]