Recombinant allergens: the present and the future.
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ABSTRACT:
SUBMITTER: Jutel M
PROVIDER: S-EPMC3660775 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Publications
Recombinant allergens: the present and the future.
Jutel Marek M Solarewicz-Madejek Katarzyna K Smolinska Sylwia S
Human vaccines & immunotherapeutics 20121001 10
Allergen specific immunotherapy (SIT) is the only known causative treatment of allergic diseases. Recombinant allergen-based vaccination strategies arose from a strong need to both to improve safety and enhance efficacy of SIT. In addition, new vaccines can be effective in allergies including food allergy or atopic dermatitis, which poorly respond to the current treatment with allergen extracts. A number of successful clinical studies with both wild-type and hypoallergenic derivatives of recombi ...[more]
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