Ontology highlight
ABSTRACT:
SUBMITTER: Chaudhury S
PROVIDER: S-EPMC3660882 | biostudies-literature | 2013 May
REPOSITORIES: biostudies-literature
Chaudhury Sukanya S Battaile Kevin P KP Lovell Scott S Plano Gregory V GV De Guzman Roberto N RN
Acta crystallographica. Section F, Structural biology and crystallization communications 20130427 Pt 5
The human pathogen Yersinia pestis requires the assembly of the type III secretion system (T3SS) for virulence. The structural component of the T3SS contains an external needle and a tip complex, which is formed by LcrV in Y. pestis. The structure of an LcrV triple mutant (K40A/D41A/K42A) in a C273S background has previously been reported to 2.2 Å resolution. Here, the crystal structure of LcrV without the triple mutation in a C273S background is reported at a higher resolution of 1.65 Å. Overal ...[more]