Ontology highlight
ABSTRACT:
SUBMITTER: Kubiak-Ossowska K
PROVIDER: S-EPMC3662390 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Kubiak-Ossowska Karina K Mulheran Paul A PA
The journal of physical chemistry. B 20110624 28
Multiprotein adsorption of hen egg white lysozyme at a model charged ionic surface is studied using fully atomistic molecular dynamics simulations. Simulations with two, three, and five proteins, in various orientations with respect the surface, are performed over a 100 ns time scale. Mutated proteins with point mutations at the major (Arg128 and Arg125) and minor (Arg68) surface adsorption sites are also studied. The 100 ns time scale used is sufficient to observe protein translations, rotation ...[more]