Predictors of progression in albuminuria in the general population: results from the PREVEND cohort.

ABSTRACT:

Background

Urinary albumin excretion is known to be independently associated with progression of renal and cardiovascular disease. The aim of this study was to identify predictors for progression in albuminuria in the general population.

Methods

Data were used of the first 4 screening rounds of a community-based prospective cohort study (PREVEND). Included were 5,825 subjects that at baseline had no known renal disease or macroalbuminuria. Subjects were defined as having progressive albuminuria when they belonged to the quintile of subjects with highest absolute increase in urinary albumin excretion per year and a urinary albumin excretion during the last screening in which they participated of ≥150 mg/24 h. Change in urinary albumin excretion per year was calculated as last

SUBMITTER: Scheven L 

PROVIDER: S-EPMC3664562 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature