Regenerative electronic biosensors using supramolecular approaches.
Ontology highlight
ABSTRACT:
SUBMITTER: Duan X
PROVIDER: S-EPMC3665757 | biostudies-literature | 2013 May
REPOSITORIES: biostudies-literature
Publications
Regenerative electronic biosensors using supramolecular approaches.
Duan Xuexin X Rajan Nitin K NK Routenberg David A DA Huskens Jurriaan J Reed Mark A MA
ACS nano 20130408 5
A supramolecular interface for Si nanowire FETs has been developed with the aim of creating regenerative electronic biosensors. The key to the approach is Si-NWs functionalized with β-cyclodextrin (β-CD), to which receptor moieties can be attached with an orthogonal supramolecular linker. Here we demonstrate full recycling using the strongest biomolecular system known, streptavidin (SAv)-biotin. The bound SAv and the linkers can be selectively removed from the surface through competitive desorpt ...[more]
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