Bioactive factors for tissue regeneration: state of the art.
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ABSTRACT:
SUBMITTER: Ohba S
PROVIDER: S-EPMC3666524 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Publications
Bioactive factors for tissue regeneration: state of the art.
Ohba Shinsuke S Hojo Hironori H Chung Ung-Il UI
Muscles, ligaments and tendons journal 20120701 3
THERE ARE THREE COMPONENTS FOR THE CREATION OF NEW TISSUES: cell sources, scaffolds, and bioactive factors. Unlike conventional medical strategies, regenerative medicine requires not only analytical approaches but also integrative ones. Basic research has identified a number of bioactive factors that are necessary, but not sufficient, for organogenesis. In skeletal development, these factors include bone morphogenetic proteins (BMPs), transforming growth factor β TGF-β, Wnts, hedgehogs (Hh), fib ...[more]
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