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Varicella-like cutaneous toxoplasmosis in a patient with aplastic anemia.

ABSTRACT: A 60-year-old patient with aplastic anemia presented with vesicular varicella-like skin lesions on her face, arms, legs, back, and abdomen. However, diagnosis for herpetic infection was negative. Findings of a skin biopsy led to a tentative histologic diagnosis of toxoplasmosis, and infection with Toxoplasma gondii was confirmed by immunohistochemistry and PCR. Cutaneous toxoplasmosis is a rare finding in immunocompromised patients and might mimic other infectious diseases, and vesicular lesions associated with toxoplasmosis have not been reported previously.

SUBMITTER: Zimmermann S

PROVIDER: S-EPMC3666818 | biostudies-literature | 2013 Apr

REPOSITORIES: biostudies-literature

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Varicella-like cutaneous toxoplasmosis in a patient with aplastic anemia.

Zimmermann Stefan S Hadaschik Eva E Dalpke Alexander A Hassel Jessica C JC Ajzenberg Daniel D Tenner-Racz Klara K Lehners Nicola N Kapaun Annette A Schnitzler Paul P

Journal of clinical microbiology 20130206 4

A 60-year-old patient with aplastic anemia presented with vesicular varicella-like skin lesions on her face, arms, legs, back, and abdomen. However, diagnosis for herpetic infection was negative. Findings of a skin biopsy led to a tentative histologic diagnosis of toxoplasmosis, and infection with Toxoplasma gondii was confirmed by immunohistochemistry and PCR. Cutaneous toxoplasmosis is a rare finding in immunocompromised patients and might mimic other infectious diseases, and vesicular lesions ...[more]

PMID: 23390283

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