Ontology highlight
ABSTRACT:
SUBMITTER: Kamieniak MM
PROVIDER: S-EPMC3668473 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Kamieniak M M MM Muñoz-Repeto I I Rico D D Osorio A A Urioste M M García-Donas J J Hernando S S Robles-Díaz L L Ramón Y Cajal T T Cazorla A A Sáez R R García-Bueno J M JM Domingo S S Borrego S S Palacios J J van de Wiel M A MA Ylstra B B Benítez J J García M J MJ
British journal of cancer 20130404 8
<h4>Background</h4>Few studies have attempted to characterise genomic changes occurring in hereditary epithelial ovarian carcinomas (EOCs) and inconsistent results have been obtained. Given the relevance of DNA copy number alterations in ovarian oncogenesis and growing clinical implications of the BRCA-gene status, we aimed to characterise the genomic profiles of hereditary and sporadic ovarian tumours.<h4>Methods</h4>High-resolution array Comparative Genomic Hybridisation profiling of 53 famili ...[more]