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Generation of a library of non-toxic quantum dots for cellular imaging and siRNA delivery.

ABSTRACT: The development of non-toxic quantum dots and further investigation of their composition-dependent cytotoxicity in a high-throughput manner have been critical challenges for biomedical imaging and gene delivery. Herein, we report a rapid sonochemical synthetic methodology for generating a library of highly biocompatible ZnS-AgInS(2) (ZAIS) quantum dots for cellular imaging and siRNA delivery.

SUBMITTER: Subramaniam P

PROVIDER: S-EPMC3668976 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature

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Generation of a library of non-toxic quantum dots for cellular imaging and siRNA delivery.

Subramaniam Prasad P Lee Seung Jae SJ Shah Shreyas S Patel Sahishnu S Starovoytov Valentin V Lee Ki-Bum KB

Advanced materials (Deerfield Beach, Fla.) 20120629 29

The development of non-toxic quantum dots and further investigation of their composition-dependent cytotoxicity in a high-throughput manner have been critical challenges for biomedical imaging and gene delivery. Herein, we report a rapid sonochemical synthetic methodology for generating a library of highly biocompatible ZnS-AgInS(2) (ZAIS) quantum dots for cellular imaging and siRNA delivery. ...[more]

PMID: 22744954

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