Ontology highlight
ABSTRACT:
SUBMITTER: Luo R
PROVIDER: S-EPMC3669295 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Luo Ruibang R Wong Thomas T Zhu Jianqiao J Liu Chi-Man CM Zhu Xiaoqian X Wu Edward E Lee Lap-Kei LK Lin Haoxiang H Zhu Wenjuan W Cheung David W DW Ting Hing-Fung HF Yiu Siu-Ming SM Peng Shaoliang S Yu Chang C Li Yingrui Y Li Ruiqiang R Lam Tak-Wah TW
PloS one 20130531 5
To tackle the exponentially increasing throughput of Next-Generation Sequencing (NGS), most of the existing short-read aligners can be configured to favor speed in trade of accuracy and sensitivity. SOAP3-dp, through leveraging the computational power of both CPU and GPU with optimized algorithms, delivers high speed and sensitivity simultaneously. Compared with widely adopted aligners including BWA, Bowtie2, SeqAlto, CUSHAW2, GEM and GPU-based aligners BarraCUDA and CUSHAW, SOAP3-dp was found t ...[more]