Ontology highlight
ABSTRACT:
SUBMITTER: Nguyet MN
PROVIDER: S-EPMC3670336 | biostudies-literature | 2013 May
REPOSITORIES: biostudies-literature
Nguyet Minh Nguyen MN Duong Thi Hue Kien TH Trung Vu Tuan VT Nguyen Than Ha Quyen TH Tran Chau N B CN Long Vo Thi VT Dui Le Thi le T Nguyen Hoa Lan HL Farrar Jeremy J JJ Holmes Edward C EC Rabaa Maia A MA Bryant Juliet E JE Nguyen Truong Thanh TT Nguyen Huong Thi Cam HT Nguyen Lan Thi Hong LT Pham Mai Phuong MP Nguyen Hung The HT Luong Tai Thi Hue TT Wills Bridget B Nguyen Chau Van Vinh CV Wolbers Marcel M Simmons Cameron P CP
Proceedings of the National Academy of Sciences of the United States of America 20130514 22
Dengue is the most prevalent arboviral disease of humans. The host and virus variables associated with dengue virus (DENV) transmission from symptomatic dengue cases (n = 208) to Aedes aegypti mosquitoes during 407 independent exposure events was defined. The 50% mosquito infectious dose for each of DENV-1-4 ranged from 6.29 to 7.52 log10 RNA copies/mL of plasma. Increasing day of illness, declining viremia, and rising antibody titers were independently associated with reduced risk of DENV trans ...[more]