Ontology highlight
ABSTRACT:
SUBMITTER: Belsky DW
PROVIDER: S-EPMC3671353 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Belsky Daniel W DW Moffitt Terrie E TE Sugden Karen K Williams Benjamin B Houts Renate R McCarthy Jeanette J Caspi Avshalom A
Biodemography and social biology 20130101 1
Multi-locus profiles of genetic risk, so-called "genetic risk scores," can be used to translate discoveries from genome-wide association studies into tools for population health research. We developed a genetic risk score for obesity from results of 16 published genome-wide association studies of obesity phenotypes in European-descent samples. We then evaluated this genetic risk score using data from the Atherosclerosis Risk in Communities (ARIC) cohort GWAS sample (N = 10,745, 55% female, 77% w ...[more]