Ontology highlight
ABSTRACT:
SUBMITTER: Fallon BP
PROVIDER: S-EPMC3672150 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Fallon Brian P BP Curnutte Bryan B Maupin Kevin A KA Partyka Katie K Choi Sunguk S Brand Randall E RE Langmead Christopher J CJ Tembe Waibhav W Haab Brian B BB
PloS one 20130604 6
The development of accurate clinical biomarkers has been challenging in part due to the diversity between patients and diseases. One approach to account for the diversity is to use multiple markers to classify patients, based on the concept that each individual marker contributes information from its respective subclass of patients. Here we present a new strategy for developing biomarker panels that accounts for completely distinct patient subclasses. Marker State Space (MSS) defines "marker sta ...[more]