Ontology highlight
ABSTRACT:
SUBMITTER: Alliegro MC
PROVIDER: S-EPMC3672282 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Alliegro Mark C MC Alliegro Mary Anne MA
RNA biology 20130116 3
The nucleolinus is a nuclear subcompartment long ago posited to play a role in cell division. In a recent study using surf clam oocytes, cytoplasmic foci containing a nucleolinar protein were shown to later recruit γ-tubulin, identifying them as centrosomal precursors. (1) We now demonstrate the presence of structural RNAs from the nucleolinus in these procentrosomes. They include the well-known but poorly understood rRNA-transcribed spacer regions. In situ hybridization revealed a specific and ...[more]