Ontology highlight
ABSTRACT:
SUBMITTER: Sultan SZ
PROVIDER: S-EPMC3676011 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
Sultan Syed Z SZ Manne Akarsh A Stewart Philip E PE Bestor Aaron A Rosa Patricia A PA Charon Nyles W NW Motaleb M A MA
Infection and immunity 20130325 6
The Lyme disease spirochete, Borrelia burgdorferi, exists in a zoonotic cycle involving an arthropod tick and mammalian host. Dissemination of the organism within and between these hosts depends upon the spirochete's ability to traverse through complex tissues. Additionally, the spirochete outruns the host immune cells while migrating through the dermis, suggesting the importance of B. burgdorferi motility in evading host clearance. B. burgdorferi's periplasmic flagellar filaments are composed p ...[more]