Salt loading in canola oil fed SHRSP rats induces endothelial dysfunction.
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ABSTRACT:
SUBMITTER: Papazzo A
PROVIDER: S-EPMC3676377 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
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Salt loading in canola oil fed SHRSP rats induces endothelial dysfunction.
Papazzo Annateresa A Conlan Xavier A XA Lexis Louise L Charchar Fadi J FJ Lewandowski Paul A PA
PloS one 20130607 6
This study aimed to determine if 50 days of canola oil intake in the absence or presence of salt loading affects: (1) antioxidant and oxidative stress markers, (2) aortic mRNA of NADPH oxidase (NOX) subunits and superoxide dismutase (SOD) isoforms and (3) endothelial function in SHRSP rats. SHRSP rats were fed a diet containing 10 wt/wt% soybean oil or 10 wt/wt% canola oil, and given tap water or water containing 1% NaCl for 50 days. Without salt, canola oil significantly increased RBC SOD, plas ...[more]
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