The angiotensin converting enzyme insertion/deletion polymorphism alters the response of muscle energy supply lines to exercise.

ABSTRACT: The presence of a silencing sequence (the I-allele) in the gene for the upstream regulator of blood flow, angiotensin I-converting enzyme (ACE), is associated with superior endurance performance and its trainability. We tested in a retrospective study with 36 Caucasian men of Swiss descent whether carriers of the ACE I-allele demonstrate a modified adaptive response of energy supply lines in knee extensor muscle, and aerobic fitness, to endurance training based on 6 weeks of supervised bicycle exercise or 6 months of self-regulated running (p value

SUBMITTER: Vaughan D 

PROVIDER: S-EPMC3677975 | biostudies-literature |

REPOSITORIES: biostudies-literature