3D-printed devices for continuous-flow organic chemistry.
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ABSTRACT:
SUBMITTER: Dragone V
PROVIDER: S-EPMC3678713 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Publications
3D-printed devices for continuous-flow organic chemistry.
Dragone Vincenza V Sans Victor V Rosnes Mali H MH Kitson Philip J PJ Cronin Leroy L
Beilstein journal of organic chemistry 20130516
We present a study in which the versatility of 3D-printing is combined with the processing advantages of flow chemistry for the synthesis of organic compounds. Robust and inexpensive 3D-printed reactionware devices are easily connected using standard fittings resulting in complex, custom-made flow systems, including multiple reactors in a series with in-line, real-time analysis using an ATR-IR flow cell. As a proof of concept, we utilized two types of organic reactions, imine syntheses and imine ...[more]
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