Ontology highlight
ABSTRACT:
SUBMITTER: Yenugonda VM
PROVIDER: S-EPMC3679116 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Yenugonda Venkata Mahidhar VM Kong Yali Y Deb Tushar B TB Yang Yonghong Y Riggins Rebecca B RB Brown Milton L ML
Cancer biology & therapy 20120801 10
Resveratrol (RSV), a natural compound present in the skin and seeds of red grapes, is considered a phytoestrogen and has structural similarity to the synthetic estrogen diethylstilbestrol. RSV inhibits tumor cell growth in estrogen receptor-positive (ER+) and negative (ER-) breast cancer cell lines resulting in cell specific regulation of the G1/S and G2/M stages of the cell cycle. However apoptotic cell death was only observed in ER+ MCF-7 cells. In this study, we designed and synthesized boron ...[more]