Dataset Information

Impact of endometriosis on quality of life and work productivity: a multicenter study across ten countries.

ABSTRACT:

Objective

To assess the impact of endometriosis on health-related quality of life (HRQoL) and work productivity.

Design

Multicenter cross-sectional study with prospective recruitment.

Setting

Sixteen clinical centers in ten countries.

Patient(s)

A total of 1,418 premenopausal women, aged 18-45 years, without a previous surgical diagnosis of endometriosis, having laparoscopy to investigate symptoms or to be sterilized.

Intervention(s)

None.

Main outcome measure(s)

Diagnostic delay, HRQoL, and work productivity.

Result(s)

There was a delay of 6.7 years, principally in primary care, between onset of symptoms and a surgical diagnosis of endometriosis, which was longer in centers where women received predominantly state-funded health care (8.3 vs. 5.5 years). Delay was positively associated with the number of pelvic symptoms (chronic pelvic pain, dysmenorrhoea, dyspareunia, and heavy periods) and a higher body mass index. Physical HRQoL was significantly reduced in affected women compared with those with similar symptoms and no endometriosis. Each affected woman lost on average 10.8 hours (SD 12.2) of work weekly, mainly owing to reduced effectiveness while working. Loss of work productivity translated into significant costs per woman/week, from US$4 in Nigeria to US$456 in Italy.

Conclusion(s)

Endometriosis impairs HRQoL and work productivity across countries and ethnicities, yet women continue to experience diagnostic delays in primary care. A higher index of suspicion is needed to expedite specialist assessment of symptomatic women. Future research should seek to clarify pain mechanisms in relation to endometriosis severity.

SUBMITTER: Nnoaham KE

PROVIDER: S-EPMC3679489 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Impact of endometriosis on quality of life and work productivity: a multicenter study across ten countries.

Nnoaham Kelechi E KE Hummelshoj Lone L Webster Premila P d'Hooghe Thomas T de Cicco Nardone Fiorenzo F de Cicco Nardone Carlo C Jenkinson Crispin C Kennedy Stephen H SH Zondervan Krina T KT

Fertility and sterility 20110630 2

<h4>Objective</h4>To assess the impact of endometriosis on health-related quality of life (HRQoL) and work productivity.<h4>Design</h4>Multicenter cross-sectional study with prospective recruitment.<h4>Setting</h4>Sixteen clinical centers in ten countries.<h4>Patient(s)</h4>A total of 1,418 premenopausal women, aged 18-45 years, without a previous surgical diagnosis of endometriosis, having laparoscopy to investigate symptoms or to be sterilized.<h4>Intervention(s)</h4>None.<h4>Main outcome meas ...[more]

PMID: 21718982

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Dataset Information

Impact of endometriosis on quality of life and work productivity: a multicenter study across ten countries.

Objective

Design

Setting

Patient(s)

Intervention(s)

Main outcome measure(s)

Result(s)

Conclusion(s)

Publications

Impact of endometriosis on quality of life and work productivity: a multicenter study across ten countries.

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