Ontology highlight
ABSTRACT:
SUBMITTER: Dudnik AS
PROVIDER: S-EPMC3679922 | biostudies-literature | 2008 Apr
REPOSITORIES: biostudies-literature
Organic letters 20080301 7
A novel gold(I)-catalyzed cycloisomerization of propargylic esters leading to unsymmetrically substituted naphthalenes has been developed. This cascade reaction involves an unprecedented tandem sequence of 1,3- and 1,2-migration of two different migrating groups. It is believed that this transformation likely proceeds via the formation of 1,3-diene intermediate or its precursor, which upon cyclization and aromatization steps transforms into the naphthalene core. ...[more]