Ontology highlight
ABSTRACT:
SUBMITTER: den Hoed M
PROVIDER: S-EPMC3680864 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
den Hoed M M Luan J J Langenberg C C Cooper C C Sayer A A AA Jameson K K Kumari M M Kivimaki M M Hingorani A D AD Grøntved A A Khaw K-T KT Ekelund U U Wareham N J NJ Loos R J F RJ
International journal of obesity (2005) 20120320 2
<h4>Background</h4>Meta-analysis of case-control genome-wide association studies (GWAS) for early onset and morbid obesity identified four variants in/near the PRL, PTER, MAF and NPC1 genes.<h4>Objective</h4>We aimed to validate association of these variants with obesity-related traits in population-based samples.<h4>Design</h4>Genotypes and anthropometric traits were available in up to 31 083 adults from the Fenland, EPIC-Norfolk, Whitehall II, Ely and Hertfordshire studies and in 2042 children ...[more]