Low protein nitrogen appearance as a surrogate of low dietary protein intake is associated with higher all-cause mortality in maintenance hemodialysis patients.
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ABSTRACT:
SUBMITTER: Ravel VA
PROVIDER: S-EPMC3681544 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
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Low protein nitrogen appearance as a surrogate of low dietary protein intake is associated with higher all-cause mortality in maintenance hemodialysis patients.
Ravel Vanessa A VA Molnar Miklos Z MZ Streja Elani E Kim Jun Chul JC Victoroff Alla A Jing Jennie J Benner Debbie D Norris Keith C KC Kovesdy Csaba P CP Kopple Joel D JD Kalantar-Zadeh Kamyar K
The Journal of nutrition 20130522 7
To determine the association between all-cause mortality and dietary protein intake in patients with chronic kidney disease, we performed a large-scale, 8-y prospective cohort study in 98,489 maintenance hemodialysis patients from a multicenter dialysis care provider. Compared with the reference level (60 to <70 g/d), low protein nitrogen appearance (PNA) levels [<30 g/d, HR: 1.40 (95% CI: 1.30, 1.50); 30 to <40 g/d, HR: 1.33 (95% CI: 1.28, 1.39)] was associated with higher all-cause mortality, ...[more]
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