Ontology highlight
ABSTRACT:
SUBMITTER: Lee SI
PROVIDER: S-EPMC3684051 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
Lee Sue I SI Conrad Travis T Jones Sherri M SM Lagziel Ayala A Starost Matthew F MF Belyantseva Inna A IA Friedman Thomas B TB Morell Robert J RJ
Hearing research 20130322
KCNA10 is a voltage gated potassium channel that is expressed in the inner ear. The localization and function of KCNA10 was studied in a mutant mouse, B6-Kcna10(TM45), in which the single protein coding exon of Kcna10 was replaced with a beta-galactosidase reporter cassette. Under the regulatory control of the endogenous Kcna10 promoter and enhancers, beta-galactosidase was expressed in hair cells of the vestibular organs and the organ of Corti. KCNA10 expression develops in opposite tonotopic g ...[more]