Genetic risk factors for pancreatic disorders.
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ABSTRACT:
SUBMITTER: Whitcomb DC
PROVIDER: S-EPMC3684061 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
Publications
A combination of genetic, environmental, and metabolic factors contribute to the development and recurrence of acute and chronic pancreatitis; information on all of these is required to manage patients effectively. For example, variants that affect regulation of the protease, serine (PRSS)1-PRSS2, and claudin (CLDN)2 loci, rather than their coding sequences, interact with other genetic and environmental factors to affect disease development. New strategies are needed to use these data and determ ...[more]
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